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Estrogen Elicits Cytochrome P450–Mediated Flow-Induced Dilation of Arterioles in NO Deficiency: Role of PI3K-Akt Phosphorylation in Genomic Regulation

This study investigated the mechanisms responsible for the estrogen-dependent, cytochrome P450 (CYP)–mediated dilator responses to shear stress in arterioles of NO-deficient female rats and mice. Flow-induced dilation (FID) was assessed in isolated arterioles from N(G)-nitro-l-arginine methyl ester...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Huang, An, Sun, Dong, Wu, Zhiping, Yan, Changdong, Carroll, Mairead A., Jiang, Houli, Falck, John R., Kaley, Gabor
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536912/
https://ncbi.nlm.nih.gov/pubmed/14670845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000111525.96232.46
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