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Estrogen Elicits Cytochrome P450–Mediated Flow-Induced Dilation of Arterioles in NO Deficiency: Role of PI3K-Akt Phosphorylation in Genomic Regulation
This study investigated the mechanisms responsible for the estrogen-dependent, cytochrome P450 (CYP)–mediated dilator responses to shear stress in arterioles of NO-deficient female rats and mice. Flow-induced dilation (FID) was assessed in isolated arterioles from N(G)-nitro-l-arginine methyl ester...
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| Pubblicato in: | Circ Res |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536912/ https://ncbi.nlm.nih.gov/pubmed/14670845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000111525.96232.46 |
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