Unique Toll-Like Receptor 4 Activation by NAMPT/PBEF Induces NFκB Signaling and Inflammatory Lung Injury

Ventilator-induced inflammatory lung injury (VILI) is mechanistically linked to increased NAMPT transcription and circulating levels of nicotinamide phosphoribosyl-transferase (NAMPT/PBEF). Although VILI severity is attenuated by reduced NAMPT/PBEF bioavailability, the precise contribution of NAMPT/...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Camp, Sara M., Ceco, Ermelinda, Evenoski, Carrie L., Danilov, Sergei M., Zhou, Tong, Chiang, Eddie T., Moreno-Vinasco, Liliana, Mapes, Brandon, Zhao, Jieling, Gursoy, Gamze, Brown, Mary E., Adyshev, Djanybek M., Siddiqui, Shahid S., Quijada, Hector, Sammani, Saad, Letsiou, Eleftheria, Saadat, Laleh, Yousef, Mohammed, Wang, Ting, Liang, Jie, Garcia, Joe G. N.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536637/
https://ncbi.nlm.nih.gov/pubmed/26272519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13135
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы