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Enzymatically Generated CRISPR Libraries for Genome Labeling and Screening
CRISPR-based technologies have emerged as powerful tools to alter genomes and mark chromosomal loci, but an inexpensive method for generating large numbers of RNA guides for whole genome screening and labeling is lacking. Using a method that permits library construction from any source of DNA, we ge...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536113/ https://ncbi.nlm.nih.gov/pubmed/26212133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.06.003 |
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