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Identification of deleterious nsSNPs in α, μ, π and θ class of GST family and their influence on protein structure

GST family genes have a critical role in xenobiotic metabolism and drug resistance. Among the GST family the GST-μ, GST-π, GST-α and GST-θ are the most abundant classes and have a major role in the carcinogen detoxification process. Nevertheless the activity of these enzymes may differ due to polymo...

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Publicat a:Genom Data
Autors principals: Yadav, P., Chatterjee, A., Bhattacharjee, A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535831/
https://ncbi.nlm.nih.gov/pubmed/26484073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gdata.2014.03.004
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