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Resistance to receptor tyrosine kinase inhibition in cancer: molecular mechanisms and therapeutic strategies
Drug resistance is a major factor that limits the efficacy of targeted cancer therapies. In this review, we discuss the main known mechanisms of resistance to receptor tyrosine kinase inhibitors, which are the most prevalent class of targeted therapeutic agent in current clinical use. Here we focus...
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| Udgivet i: | Front Med |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4535791/ https://ncbi.nlm.nih.gov/pubmed/25957263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11684-015-0396-9 |
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