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Bcl2 inhibition of mitochondrial DNA repair

BACKGROUND: Accumulation of mitochondrial DNA (mtDNA) damage could enhance the frequency of mitochondrial mutations and promote a variety of mitochondria-related diseases, including cancer. However, the mechanism(s) involved are not fully understood. METHODS: Quantitative extended length PCR was use...

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Publicat a:BMC Cancer
Autors principals: Xie, Maohua, Doetsch, Paul W., Deng, Xingming
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535531/
https://ncbi.nlm.nih.gov/pubmed/26268226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1594-1
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