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Bcl2 inhibition of mitochondrial DNA repair

BACKGROUND: Accumulation of mitochondrial DNA (mtDNA) damage could enhance the frequency of mitochondrial mutations and promote a variety of mitochondria-related diseases, including cancer. However, the mechanism(s) involved are not fully understood. METHODS: Quantitative extended length PCR was use...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Xie, Maohua, Doetsch, Paul W., Deng, Xingming
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535531/
https://ncbi.nlm.nih.gov/pubmed/26268226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1594-1
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