Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility

BACKGROUND: Leukocyte migration is critical for the infiltration of monocytes and accumulation of monocyte derived macrophages in inflammation. Considering that Hck and Fgr are instrumental in this process, their impact on atherosclerosis and on lesion inflammation and stability was evaluated. METHO...

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Publicado en:Circulation
Main Authors: Medina, Indira, Cougoule, Céline, Drechsler, Maik, Bermudez, Beatriz, Koenen, Rory R., Sluimer, Judith, Wolfs, Ine, Döring, Yvonne, Herias, Veronica, Gijbels, Marjon, Bot, Ilze, de Jager, Saskia, Weber, Christian, Cleutjens, Jack, van Berkel, Theo J.C., Sikkink, Kees-Jan, Mócsai, Atilla, Maridonneau-Parini, Isabelle, Soehnlein, Oliver, Biessen, Erik A.L.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535360/
https://ncbi.nlm.nih.gov/pubmed/26068045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.012316
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