Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility

BACKGROUND: Leukocyte migration is critical for the infiltration of monocytes and accumulation of monocyte derived macrophages in inflammation. Considering that Hck and Fgr are instrumental in this process, their impact on atherosclerosis and on lesion inflammation and stability was evaluated. METHO...

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Publicado no:Circulation
Principais autores: Medina, Indira, Cougoule, Céline, Drechsler, Maik, Bermudez, Beatriz, Koenen, Rory R., Sluimer, Judith, Wolfs, Ine, Döring, Yvonne, Herias, Veronica, Gijbels, Marjon, Bot, Ilze, de Jager, Saskia, Weber, Christian, Cleutjens, Jack, van Berkel, Theo J.C., Sikkink, Kees-Jan, Mócsai, Atilla, Maridonneau-Parini, Isabelle, Soehnlein, Oliver, Biessen, Erik A.L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535360/
https://ncbi.nlm.nih.gov/pubmed/26068045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.012316
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