Runx2 Regulates Endochondral Ossification through Control of Chondrocyte Proliferation and Differentiation

Synthesis of cartilage by chondrocytes is an obligatory step for endochondral ossification. Global deletion of the Runx2 gene results in complete failure of the ossification process, but the underlying cellular and molecular mechanisms are not fully known. Here, we elucidated Runx2 regulatory contro...

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Bibliographic Details
Published in:J Bone Miner Res
Main Authors: Chen, Haiyan, Ghori-Javed, Farah Y., Rashid, Harunur, Adhami, Mitra D., Serra, Rosa, Gutierrez, Soraya E., Javed, Amjad
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535340/
https://ncbi.nlm.nih.gov/pubmed/24862038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2287
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