FAK regulates cardiomyocyte survival following ischemia/reperfusion

Myocyte apoptosis is central to myocardial dysfunction following ischemia/reperfusion (I/R) and during the transition from hypertrophy to heart failure. Focal adhesion kinase (FAK), a non-receptor tyrosine kinase regulates adhesion-dependent survival signals and unopposed FAK activation has been lin...

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Publicado en:J Mol Cell Cardiol
Autores principales: Hakim, Zeenat S., DiMichele, Laura A., Rojas, Mauricio, Meredith, Dane, Mack, Christopher P., Taylor, Joan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535182/
https://ncbi.nlm.nih.gov/pubmed/19028502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.10.017
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