Novel Paraoxonase 2-Dependent Mechanism Mediating the Biological Effects of the Pseudomonas aeruginosa Quorum-Sensing Molecule N-(3-Oxo-Dodecanoyl)-l-Homoserine Lactone

Pseudomonas aeruginosa produces N-(3-oxo-dodecanoyl)-l-homoserine lactone (3OC12), a crucial signaling molecule that elicits diverse biological responses in host cells thought to subvert immune defenses. The mechanism mediating many of these responses remains unknown. The intracellular lactonase par...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Horke, Sven, Xiao, Junhui, Schütz, Eva-Maria, Kramer, Gerald L., Wilgenbus, Petra, Witte, Ines, Selbach, Moritz, Teiber, John F.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534671/
https://ncbi.nlm.nih.gov/pubmed/26056385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00141-15
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