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A Human-Specific α7-Nicotinic Acetylcholine Receptor Gene in Human Leukocytes: Identification, Regulation and the Consequences of CHRFAM7A Expression

The human genome contains a variant form of the α7-nicotinic acetylcholine receptor (α7nAChR) gene that is uniquely human. This CHRFAM7A gene arose during human speciation and recent data suggests that its expression alters ligand tropism of the normally homopentameric human α7-AChR ligand-gated cel...

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Dades bibliogràfiques
Publicat a:Mol Med
Autors principals: Costantini, Todd W, Dang, Xitong, Yurchyshyna, Maryana V, Coimbra, Raul, Eliceiri, Brian P, Baird, Andrew
Format: Artigo
Idioma:Inglês
Publicat: ScholarOne 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534468/
https://ncbi.nlm.nih.gov/pubmed/25860877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00018
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