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Up-regulation of the human-specific CHRFAM7A gene in inflammatory bowel disease

Background: The α7-subunit of the α7-nicotinic acetylcholine receptor (α7-nAChR) is an obligatory intermediate for the anti-inflammatory effects of the vagus nerve. But in humans, there exists a second gene called CHRFAM7A that encodes a dominant negative α7-nAChR inhibitor. Here, we investigated wh...

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Dettagli Bibliografici
Pubblicato in:BBA Clin
Autori principali: Baird, Andrew, Coimbra, Raul, Dang, Xitong, Eliceiri, Brian P., Costantini, Todd W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802402/
https://ncbi.nlm.nih.gov/pubmed/27051591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbacli.2015.12.003
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