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iPSC model of CHRFAM7A effect on α7 nicotinic acetylcholine receptor function in the human context
The α7 nicotinic acetylcholine receptor (α7nAChR) has been a promising target for diseases affecting cognition and higher cortical functions; however, the effect observed in animal models failed to translate into human clinical trials identifying a translational gap. CHRFAM7A is a human-specific fus...
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| Publicado no: | Transl Psychiatry |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6358606/ https://ncbi.nlm.nih.gov/pubmed/30710073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0375-z |
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