Differentiate or Die: 3-Bromopyruvate and Pluripotency in Mouse Embryonic Stem Cells

BACKGROUND: Pluripotent embryonic stem cells grown under standard conditions (ESC) have a markedly glycolytic profile, which is shared with many different types of cancer cells. Thus, some therapeutic strategies suggest that pharmacologically shifting cancer cells towards an oxidative phenotype, usi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Rodrigues, Ana Sofia, Pereira, Sandro L., Correia, Marcelo, Gomes, Andreia, Perestrelo, Tânia, Ramalho-Santos, João
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534445/
https://ncbi.nlm.nih.gov/pubmed/26266544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135617
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