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Differentiate or Die: 3-Bromopyruvate and Pluripotency in Mouse Embryonic Stem Cells
BACKGROUND: Pluripotent embryonic stem cells grown under standard conditions (ESC) have a markedly glycolytic profile, which is shared with many different types of cancer cells. Thus, some therapeutic strategies suggest that pharmacologically shifting cancer cells towards an oxidative phenotype, usi...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4534445/ https://ncbi.nlm.nih.gov/pubmed/26266544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135617 |
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