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Differentiate or Die: 3-Bromopyruvate and Pluripotency in Mouse Embryonic Stem Cells

BACKGROUND: Pluripotent embryonic stem cells grown under standard conditions (ESC) have a markedly glycolytic profile, which is shared with many different types of cancer cells. Thus, some therapeutic strategies suggest that pharmacologically shifting cancer cells towards an oxidative phenotype, usi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Rodrigues, Ana Sofia, Pereira, Sandro L., Correia, Marcelo, Gomes, Andreia, Perestrelo, Tânia, Ramalho-Santos, João
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534445/
https://ncbi.nlm.nih.gov/pubmed/26266544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135617
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