Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia at the clinic. Recent GWAS identified several variants associated with AF, but they account for <10% of heritability. Gene-gene interaction is assumed to account for a significant portion of missing heritability. Among GWAS loci for A...

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Publicado no:PLoS Genet
Main Authors: Huang, Yufeng, Wang, Chuchu, Yao, Yufeng, Zuo, Xiaoyu, Chen, Shanshan, Xu, Chengqi, Zhang, Hongfu, Lu, Qiulun, Chang, Le, Wang, Fan, Wang, Pengxia, Zhang, Rongfeng, Hu, Zhenkun, Song, Qixue, Yang, Xiaowei, Li, Cong, Li, Sisi, Zhao, Yuanyuan, Yang, Qin, Yin, Dan, Wang, Xiaojing, Si, Wenxia, Li, Xiuchun, Xiong, Xin, Wang, Dan, Huang, Yuan, Luo, Chunyan, Li, Jia, Wang, Jingjing, Chen, Jing, Wang, Longfei, Wang, Li, Han, Meng, Ye, Jian, Chen, Feifei, Liu, Jingqiu, Liu, Ying, Wu, Gang, Yang, Bo, Cheng, Xiang, Liao, Yuhua, Wu, Yanxia, Ke, Tie, Chen, Qiuyun, Tu, Xin, Elston, Robert, Rao, Shaoqi, Yang, Yanzong, Xia, Yunlong, Wang, Qing K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534423/
https://ncbi.nlm.nih.gov/pubmed/26267381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005393
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