Genomic Variant in CAV1 Increases Susceptibility to Coronary Artery Disease and Myocardial Infarction

BACKGROUND: The CAV1 gene encodes caveolin-1 expressed in cell types relevant to atherosclerosis. Cav-1-null mice showed a protective effect on atherosclerosis under the ApoE(−/−) background. However, it is unknown whether CAV1 is linked to CAD and MI in humans. In this study we analyzed a tagSNP fo...

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Bibliografski detalji
Izdano u:Atherosclerosis
Glavni autori: Chen, Shanshan, Wang, Xiaojing, Wang, Junhan, Zhao, Yuanyuan, Wang, Dan, Tan, Chengcheng, Fa, Jingjing, Zhang, Rongfeng, Wang, Fan, Xu, Chaoping, Huang, Yufeng, Li, Sisi, Yin, Dan, Xiong, Xin, Li, Xiuchun, Chen, Qiuyun, Tu, Xin, Yang, Yanzong, Xia, Yonglong, Xu, Chengqi, Wang, Qing K.
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764411/
https://ncbi.nlm.nih.gov/pubmed/26775120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2016.01.008
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