Mucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIV(mac251) Rectal Challenge

Many viral infections, including HIV, exhibit sex-based pathogenic differences. However, few studies have examined vaccine-related sex differences. We compared immunogenicity and protective efficacy of monomeric SIV gp120 with oligomeric SIV gp140 in a pre-clinical rhesus macaque study and explored...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Tuero, Iskra, Mohanram, Venkatramanan, Musich, Thomas, Miller, Leia, Vargas-Inchaustegui, Diego A., Demberg, Thorsten, Venzon, David, Kalisz, Irene, Kalyanaraman, V. S., Pal, Ranajit, Ferrari, Maria Grazia, LaBranche, Celia, Montefiori, David C., Rao, Mangala, Vaccari, Monica, Franchini, Genoveffa, Barnett, Susan W., Robert-Guroff, Marjorie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534401/
https://ncbi.nlm.nih.gov/pubmed/26267144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005101
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