Mucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIV(mac251) Rectal Challenge

Many viral infections, including HIV, exhibit sex-based pathogenic differences. However, few studies have examined vaccine-related sex differences. We compared immunogenicity and protective efficacy of monomeric SIV gp120 with oligomeric SIV gp140 in a pre-clinical rhesus macaque study and explored...

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Opis bibliograficzny
Wydane w:PLoS Pathog
Główni autorzy: Tuero, Iskra, Mohanram, Venkatramanan, Musich, Thomas, Miller, Leia, Vargas-Inchaustegui, Diego A., Demberg, Thorsten, Venzon, David, Kalisz, Irene, Kalyanaraman, V. S., Pal, Ranajit, Ferrari, Maria Grazia, LaBranche, Celia, Montefiori, David C., Rao, Mangala, Vaccari, Monica, Franchini, Genoveffa, Barnett, Susan W., Robert-Guroff, Marjorie
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2015
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534401/
https://ncbi.nlm.nih.gov/pubmed/26267144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005101
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