Shigella IpaB and IpaD displayed on L. lactis bacterium-like particles induce protective immunity in adult and infant mice

Shigella spp. are among the enteric pathogens with the highest attributable incidence of moderate-to-severe diarrhea in children under 5 years of age living in endemic areas. There are no vaccines available to prevent this disease. In this work, we investigated a new Shigella vaccine concept consist...

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Vydáno v:Immunol Cell Biol
Hlavní autoři: Heine, Shannon J., Franco-Mahecha, Olga L., Chen, Xiaotong, Choudhari, Shyamal, Blackwelder, William C., van Roosmalen, Maarten L., Leenhouts, Kees, Picking, Wendy L., Pasetti, Marcela F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534326/
https://ncbi.nlm.nih.gov/pubmed/25776843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2015.24
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