Anoctamin 1 (TMEM16A) is essential for testosterone-induced prostate hyperplasia

Benign prostatic hyperplasia (BPH) is characterized by an enlargement of the prostate, causing lower urinary tract symptoms in elderly men worldwide. However, the molecular mechanism underlying the pathogenesis of BPH is unclear. Anoctamin1 (ANO1) encodes a Ca(2+)-activated chloride channel (CaCC) t...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Cha, Joo Young, Wee, Jungwon, Jung, Jooyoung, Jang, Yongwoo, Lee, Byeongjun, Hong, Gyu-Sang, Chang, Beom Chul, Choi, Yoon-La, Shin, Young Kee, Min, Hye-Young, Lee, Ho-Young, Na, Tae-Young, Lee, Mi-Ock, Oh, Uhtaek
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534281/
https://ncbi.nlm.nih.gov/pubmed/26153424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423827112
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