Two helices in the third intracellular loop determine anoctamin 1 (TMEM16A) activation by calcium

Anoctamin 1 (ANO1)/TMEM16A is a Cl(−) channel activated by intracellular Ca(2+) mediating numerous physiological functions. However, little is known of the ANO1 activation mechanism by Ca(2+). Here, we demonstrate that two helices, “reference” and “Ca(2+) sensor” helices in the third intracellular l...

詳細記述

保存先:
書誌詳細
出版年:Pflugers Arch
主要な著者: Lee, Jesun, Jung, Jooyoung, Tak, Min Ho, Wee, Jungwon, Lee, Byeongjoon, Jang, Yongwoo, Chun, Hyeyeon, Yang, Dong-Jin, Yang, Young Duk, Park, Sang Ho, Han, Byung Woo, Hyun, Soonsil, Yu, Jaehoon, Cho, Hawon, Hartzell, H. Criss, Oh, Uhtaek
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2014
主題:
Ion Channels, Receptors and Transporters
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502317/
https://ncbi.nlm.nih.gov/pubmed/25231974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-014-1603-2
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料