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Physiological roles and diseases of tmem16/anoctamin proteins: are they all chloride channels?
The Tmem16 gene family was first identified by bioinformatic analysis in 2004. In 2008, it was shown independently by 3 laboratories that the first two members (Tmem16A and Tmem16B) of this 10-gene family are Ca(2+)-activated Cl(−) channels. Because these proteins are thought to have 8 transmembrane...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3756662/ https://ncbi.nlm.nih.gov/pubmed/21642943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.48 |
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