Anoctamin 1 (Tmem16A) Ca(2)(+)-activated chloride channel stoichiometrically interacts with an ezrin–radixin–moesin network

The newly discovered Ca(2+)-activated Cl(−) channel (CaCC), Anoctamin 1 (Ano1 or TMEM16A), has been implicated in vital physiological functions including epithelial fluid secretion, gut motility, and smooth muscle tone. Overexpression of Ano1 in HEK cells or Xenopus oocytes is sufficient to generate...

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Detalles Bibliográficos
Autores principales: Perez-Cornejo, Patricia, Gokhale, Avanti, Duran, Charity, Cui, Yuanyuan, Xiao, Qinghuan, Hartzell, H. Criss, Faundez, Victor
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387097/
https://ncbi.nlm.nih.gov/pubmed/22685202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200174109
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