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Anoctamin 1 (TMEM16A) is essential for testosterone-induced prostate hyperplasia

Benign prostatic hyperplasia (BPH) is characterized by an enlargement of the prostate, causing lower urinary tract symptoms in elderly men worldwide. However, the molecular mechanism underlying the pathogenesis of BPH is unclear. Anoctamin1 (ANO1) encodes a Ca(2+)-activated chloride channel (CaCC) t...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Cha, Joo Young, Wee, Jungwon, Jung, Jooyoung, Jang, Yongwoo, Lee, Byeongjun, Hong, Gyu-Sang, Chang, Beom Chul, Choi, Yoon-La, Shin, Young Kee, Min, Hye-Young, Lee, Ho-Young, Na, Tae-Young, Lee, Mi-Ock, Oh, Uhtaek
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534281/
https://ncbi.nlm.nih.gov/pubmed/26153424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423827112
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