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IL-15 receptor α signaling constrains the development of IL-17–producing γδ T cells

The development and homeostasis of γδ T cells is highly dependent on distinct cytokine networks. Here we examine the role of IL-15 and its unique receptor, IL-15Rα, in the development of IL-17–producing γδ (γδ-17) T cells. Phenotypic analysis has shown that CD44(high) γδ-17 cells express IL-15Rα and...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Colpitts, Sara L., Puddington, Lynn, Lefrançois, Leo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534247/
https://ncbi.nlm.nih.gov/pubmed/26195801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420741112
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