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IL-15 receptor α signaling constrains the development of IL-17–producing γδ T cells

The development and homeostasis of γδ T cells is highly dependent on distinct cytokine networks. Here we examine the role of IL-15 and its unique receptor, IL-15Rα, in the development of IL-17–producing γδ (γδ-17) T cells. Phenotypic analysis has shown that CD44(high) γδ-17 cells express IL-15Rα and...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Colpitts, Sara L., Puddington, Lynn, Lefrançois, Leo
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534247/
https://ncbi.nlm.nih.gov/pubmed/26195801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420741112
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