Burst pacemaker activity of the sinoatrial node in sodium–calcium exchanger knockout mice

In sinoatrial node (SAN) cells, electrogenic sodium–calcium exchange (NCX) is the dominant calcium (Ca) efflux mechanism. However, the role of NCX in the generation of SAN automaticity is controversial. To investigate the contribution of NCX to pacemaking in the SAN, we performed optical voltage map...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Torrente, Angelo G., Zhang, Rui, Zaini, Audrey, Giani, Jorge F., Kang, Jeanney, Lamp, Scott T., Philipson, Kenneth D., Goldhaber, Joshua I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534240/
https://ncbi.nlm.nih.gov/pubmed/26195795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505670112
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