c-Myc Alters Substrate Utilization and O-GlcNAc Protein Posttranslational Modifications without Altering Cardiac Function during Early Aortic Constriction

Hypertrophic stimuli cause transcription of the proto-oncogene c-Myc (Myc). Prior work showed that myocardial knockout of c-Myc (Myc) attenuated hypertrophy and decreased expression of metabolic genes after aortic constriction. Accordingly, we assessed the interplay between Myc, substrate oxidation...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ledee, Dolena, Smith, Lincoln, Bruce, Margaret, Kajimoto, Masaki, Isern, Nancy, Portman, Michael A., Olson, Aaron K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534195/
https://ncbi.nlm.nih.gov/pubmed/26266538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135262
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