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Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL)
BACKGROUND: IKZF1 deletions are an unfavorable prognostic factor in children with Philadelphia chromosome positive (Ph(+)) as well as negative (Ph(−)) acute lymphoblastic leukemia (ALL). Although IKZF1 deletions occur in 10–15% of Ph(−) ALL cases, effects of IKZF1 deletions on signaling pathways in...
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| Veröffentlicht in: | Exp Hematol Oncol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4534008/ https://ncbi.nlm.nih.gov/pubmed/26269779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-015-0017-y |
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