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SH3KBP1 binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex SHKBP1 prevents EGFR degradation by the interruption of c-Cbl-CIN85 complex
The binding of Cbl-interacting protein of 85 kDa (CIN85) to c-Cbl is important to endocytosis and degradation of epidermal growth factor receptor (EGFR). The proline-arginine motif PXXXPR in c-Cbl and SH3 domains of CIN85 are essential to this interaction. Here we demonstrated that SH3KBP1 binding p...
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| 出版年: | Cell Biochem Funct |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4534006/ https://ncbi.nlm.nih.gov/pubmed/21830225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbf.1792 |
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