Endothelial–cell FAK targeting sensitizes tumours to DNA–damaging therapy

Chemoresistance is a serious limitation of cancer treatment(1). Until recently, almost all the work done to study this limitation has been restricted to tumour cells(2). Here we identify a novel molecular mechanism by which endothelial cells regulate chemosensitivity. We establish that specific targ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nature
Main Authors: Tavora, Bernardo, Reynolds, Louise E., Batista, Silvia, Demircioglu, Fevzi, Fernandez, Isabelle, Lechertier, Tanguy, Lees, Delphine M., Wong, Ping–Pui, Alexopoulou, Annika, Elia, George, Clear, Andrew, Ledoux, Adeline, Hunter, Jill, Perkins, Neil, Gribben, John G., Hodivala–Dilke, Kairbaan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533916/
https://ncbi.nlm.nih.gov/pubmed/25079333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13541
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados