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FAK-heterozygous mice display enhanced tumour angiogenesis

Genetic ablation of endothelial Focal Adhesion Kinase (FAK) can inhibit pathological angiogenesis, suggesting that loss of endothelial FAK is sufficient to reduce neovascularisation. Here we show that reduced stromal-FAK expression in FAK-heterozygous mice unexpectedly enhances both B16F0 and CMT19T...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kostourou, Vassiliki, Lechertier, Tanguy, Reynolds, Louise E., Lees, Delphine M., Baker, Marianne, Jones, Dylan T., Tavora, Bernardo, Ramjaun, Antoine R., Birdsey, Graeme M., Robinson, Stephen D., Parsons, Maddy, Randi, Anna M., Hart, Ian R, Hodivala-Dilke, Kairbaan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712492/
https://ncbi.nlm.nih.gov/pubmed/23799510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3020
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