Hepatic Macrophage Migration and Differentiation Critical for Liver Fibrosis Is Mediated by the Chemokine Receptor C-C Motif Chemokine Receptor 8 in Mice

Chemokines critically control the infiltration of immune cells upon liver injury, thereby promoting hepatic inflammation and fibrosis. The chemokine receptor CCR8 can affect trafficking of monocytes/macrophages, monocyte-derived dendritic cells (DCs) and T-helper cell (Th) subsets, but its role in l...

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Publicat a:Hepatology
Autors principals: Heymann, Felix, Hammerich, Linda, Storch, Dunja, Bartneck, Matthias, Huss, Sebastian, Rüsseler, Vanessa, Gassler, Nikolaus, Lira, Sergio A., Luedde, Tom, Trautwein, Christian, Tacke, Frank
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533854/
https://ncbi.nlm.nih.gov/pubmed/22031018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24764
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