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Interleukin-8 Is Activated in Patients with Chronic Liver Diseases and Associated with Hepatic Macrophage Accumulation in Human Liver Fibrosis

BACKGROUND: Interleukin-8 (IL-8, CXCL8) is a potent chemoattractant for neutrophils and contributes to acute liver inflammation. Much less is known about IL-8 in chronic liver diseases (CLD), but elevated levels were reported from alcoholic and hepatitis C-related CLD. We investigated the regulation...

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Библиографические подробности
Главные авторы: Zimmermann, Henning W., Seidler, Sebastian, Gassler, Nikolaus, Nattermann, Jacob, Luedde, Tom, Trautwein, Christian, Tacke, Frank
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120868/
https://ncbi.nlm.nih.gov/pubmed/21731723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021381
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