Pharmacological Inhibition of the Chemokine CXCL16 Diminishes Liver Macrophage Infiltration and Steatohepatitis in Chronic Hepatic Injury

Non-alcoholic fatty liver disease (NAFLD) is a major cause of morbidity and mortality in developed countries, resulting in steatohepatitis (NASH), fibrosis and eventually cirrhosis. Modulating inflammatory mediators such as chemokines may represent a novel therapeutic strategy for NAFLD. We recently...

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Pubblicato in:PLoS One
Autori principali: Wehr, Alexander, Baeck, Christer, Ulmer, Florian, Gassler, Nikolaus, Hittatiya, Kanishka, Luedde, Tom, Neumann, Ulf Peter, Trautwein, Christian, Tacke, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221470/
https://ncbi.nlm.nih.gov/pubmed/25372401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112327
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