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TGF-β1 induces apoptosis of bone marrow-derived mesenchymal stem cells via regulation of mitochondrial reactive oxygen species production

Bone marrow-derived mesenchymal stem cells (BMSCs) are the most promising seed cells in regenerative medicine. Our previous study demonstrated that transforming growth factor (TGF)-β1 induced BMSC senescence in vitro. Whether TGF-β1 affects the apoptosis of BMSCs has not been examined; therefore the...

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Bibliografske podrobnosti
izdano v:Exp Ther Med
Main Authors: ZHANG, FENXI, REN, TONGMING, WU, JUNFANG
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533206/
https://ncbi.nlm.nih.gov/pubmed/26622469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2590
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