Enhanced astroglial GABA uptake attenuates tonic GABA(A) inhibition of the presympathetic hypothalamic paraventricular nucleus neurons in heart failure

γ-Aminobutyric acid (GABA) generates persistent tonic inhibitory currents (I(tonic)) and conventional inhibitory postsynaptic currents in the hypothalamic paraventricular nucleus (PVN) via activation of GABA(A) receptors (GABA(A)Rs). We investigated the pathophysiological significance of astroglial...

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Bibliografski detalji
Izdano u:J Neurophysiol
Glavni autori: Pandit, Sudip, Jo, Ji Yoon, Lee, Sang Ung, Lee, Young Jae, Lee, So Yeong, Ryu, Pan Dong, Lee, Jung Un, Kim, Hyun-Woo, Jeon, Byeong Hwa, Park, Jin Bong
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
Teme:
Nervous System Pathophysiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533111/
https://ncbi.nlm.nih.gov/pubmed/26063771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00080.2015
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