Enhanced astroglial GABA uptake attenuates tonic GABA(A) inhibition of the presympathetic hypothalamic paraventricular nucleus neurons in heart failure

γ-Aminobutyric acid (GABA) generates persistent tonic inhibitory currents (I(tonic)) and conventional inhibitory postsynaptic currents in the hypothalamic paraventricular nucleus (PVN) via activation of GABA(A) receptors (GABA(A)Rs). We investigated the pathophysiological significance of astroglial...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Pandit, Sudip, Jo, Ji Yoon, Lee, Sang Ung, Lee, Young Jae, Lee, So Yeong, Ryu, Pan Dong, Lee, Jung Un, Kim, Hyun-Woo, Jeon, Byeong Hwa, Park, Jin Bong
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Nervous System Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533111/
https://ncbi.nlm.nih.gov/pubmed/26063771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00080.2015
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