Genetic Changes in HIV-1 Gag-Protease Associated with Protease Inhibitor-Based Therapy Failure in Pediatric Patients

Studies have shown a low frequency of HIV-1 protease drug resistance mutations in patients failing protease inhibitor (PI)-based therapy. Recent studies have identified mutations in Gag as an alternate pathway for PI drug resistance in subtype B viruses. We therefore genotyped the Gag and protease g...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Giandhari, Jennifer, Basson, Adriaan E., Coovadia, Ashraf, Kuhn, Louise, Abrams, Elaine J., Strehlau, Renate, Morris, Lynn, Hunt, Gillian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Clinical Trials/Clinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533029/
https://ncbi.nlm.nih.gov/pubmed/25919760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2014.0349
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