Switching children previously exposed to nevirapine to nevirapine-based treatment after initial suppression with a protease-inhibitor-based regimen: long-term follow-up of a randomised, open-label trial

BACKGROUND: Protease inhibitor (PI)-based therapy is recommended as first-line treatment for HIV-infected infants exposed to nevirapine prophylaxis. However, long-term use poses adherence challenges, is associated with metabolic toxicities, limits second-line options, and is costly. We report long-t...

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Vydáno v:Lancet Infect Dis
Hlavní autoři: Kuhn, Louise, Coovadia, Ashraf, Strehlau, Renate, Martens, Leigh, Hu, Chih-Chi, Meyers, Tammy, Sherman, Gayle, Hunt, Gillian, Persaud, Deborah, Morris, Lynn, Tsai, Wei-Yann, Abrams, Elaine J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539971/
https://ncbi.nlm.nih.gov/pubmed/22424722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(12)70051-8
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