Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice

The male’s ability to reproduce is completely dependent on Sertoli cells. However, the mechanisms governing the functional integrity of Sertoli cells have remained largely unexplored. Here, we demonstrate that deletion of Shp2 in Sertoli cells results in infertility in mice. In Shp2 knockout mice (S...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Hu, Xiaopeng, Tang, Zhenzhou, Li, Yang, Liu, Wensheng, Zhang, Shuang, Wang, Bingyan, Tian, Yingpu, Zhao, Yinan, Ran, Hao, Liu, Wenjie, Feng, Gen-Sheng, Shuai, Jianwei, Wang, Haibin, Lu, Zhongxian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533007/
https://ncbi.nlm.nih.gov/pubmed/26265072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12982
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