Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice

The male’s ability to reproduce is completely dependent on Sertoli cells. However, the mechanisms governing the functional integrity of Sertoli cells have remained largely unexplored. Here, we demonstrate that deletion of Shp2 in Sertoli cells results in infertility in mice. In Shp2 knockout mice (S...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hu, Xiaopeng, Tang, Zhenzhou, Li, Yang, Liu, Wensheng, Zhang, Shuang, Wang, Bingyan, Tian, Yingpu, Zhao, Yinan, Ran, Hao, Liu, Wenjie, Feng, Gen-Sheng, Shuai, Jianwei, Wang, Haibin, Lu, Zhongxian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533007/
https://ncbi.nlm.nih.gov/pubmed/26265072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12982
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