Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice

The male’s ability to reproduce is completely dependent on Sertoli cells. However, the mechanisms governing the functional integrity of Sertoli cells have remained largely unexplored. Here, we demonstrate that deletion of Shp2 in Sertoli cells results in infertility in mice. In Shp2 knockout mice (S...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Hu, Xiaopeng, Tang, Zhenzhou, Li, Yang, Liu, Wensheng, Zhang, Shuang, Wang, Bingyan, Tian, Yingpu, Zhao, Yinan, Ran, Hao, Liu, Wenjie, Feng, Gen-Sheng, Shuai, Jianwei, Wang, Haibin, Lu, Zhongxian
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533007/
https://ncbi.nlm.nih.gov/pubmed/26265072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12982
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