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Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation

Here, we investigated the anticancer effect of Rhus coriaria on three breast cancer cell lines. We demonstrated that Rhus coriaria ethanolic extract (RCE) inhibits the proliferation of these cell lines in a time- and concentration-dependent manner. RCE induced senescence and cell cycle arrest at G1...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: El Hasasna, Hussain, Athamneh, Khawlah, Al Samri, Halima, Karuvantevida, Noushad, Al Dhaheri, Yusra, Hisaindee, Soleiman, Ramadan, Gaber, Al Tamimi, Nedaa, AbuQamar, Synan, Eid, Ali, Iratni, Rabah
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532997/
https://ncbi.nlm.nih.gov/pubmed/26263881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13013
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