Rhus coriaria increases protein ubiquitination, proteasomal degradation and triggers non-canonical Beclin-1-independent autophagy and apoptotic cell death in colon cancer cells

Colorectal cancer is the fourth leading cause of cancer-related deaths worldwide. Here, we investigated the anticancer effect of Rhus coriaria extract (RCE) on HT-29 and Caco-2 human colorectal cancer cells. We found that RCE significantly inhibited the viability and colony growth of colon cancer ce...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Athamneh, Khawlah, Hasasna, Hussain El, Samri, Halima Al, Attoub, Samir, Arafat, Kholoud, Benhalilou, Nehla, Rashedi, Asma Al, Dhaheri, Yusra Al, AbuQamar, Synan, Eid, Ali, Iratni, Rabah
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599689/
https://ncbi.nlm.nih.gov/pubmed/28912474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11202-3
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