Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation

Here, we investigated the anticancer effect of Rhus coriaria on three breast cancer cell lines. We demonstrated that Rhus coriaria ethanolic extract (RCE) inhibits the proliferation of these cell lines in a time- and concentration-dependent manner. RCE induced senescence and cell cycle arrest at G1...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: El Hasasna, Hussain, Athamneh, Khawlah, Al Samri, Halima, Karuvantevida, Noushad, Al Dhaheri, Yusra, Hisaindee, Soleiman, Ramadan, Gaber, Al Tamimi, Nedaa, AbuQamar, Synan, Eid, Ali, Iratni, Rabah
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532997/
https://ncbi.nlm.nih.gov/pubmed/26263881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13013
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