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Mammalian synthetic circuits with RNA binding proteins delivered by RNA
Synthetic regulatory circuits encoded on RNA rather than DNA could provide a means to control cell behavior while avoiding potentially harmful genomic integration in therapeutic applications. We create post-transcriptional circuits using RNA-binding proteins, which can be wired in a plug-and-play fa...
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| Pubblicato in: | Nat Biotechnol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532950/ https://ncbi.nlm.nih.gov/pubmed/26237515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3301 |
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