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Anatomy of protein disorder, flexibility and disease-related mutations

Integration of protein structural information with human genetic variation and pathogenic mutations is essential to understand molecular mechanisms associated with the effects of polymorphisms on protein interactions and cellular processes. We investigate occurrences of non-synonymous SNPs in ordere...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Lu, Hui-Chun, Chung, Sun Sook, Fornili, Arianna, Fraternali, Franca
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532925/
https://ncbi.nlm.nih.gov/pubmed/26322316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2015.00047
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